An earthquake registering a magnitude of 7.7 struck southern Chile, the United States Geological Survey (USGS) said.
The epicenter is said to have been in Los Lagos, some 225 kms south-west of Puerto Montt at a depth was about 15 kms.
Chile's National Emergency Office, or Onemi, said there were no immediate reports of deaths or injuries, and Onemi chief Ricardo Toro had called on Los Lagos residents to go to safe zones.
The first tidal waves were expected to arrive at the shoreline in the Los Lagos area at 1 p.m. local time, Onemi said, however, this was downgraded to 'precautions' in the regions closest to the epicentre.
Chile is often rocked by major earthquakes, including the world's strongest on record in 1960, when the southern city of Valdivia was leveled by magnitude 9.4–9.6 quake. Up to 6,000 are said to have perished, particularly after a tsunami with waves as high as 10.7 metres came in land.
In 2010, a devastating 8.8 quake decimated the region around the city of Concepcion, leaving 525 dead.